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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CHD3 All Species: 29.09
Human Site: S777 Identified Species: 53.33
UniProt: Q12873 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.25
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q12873 NP_001005271.2 2000 226592 S777 Q T I V F L Y S L Y K E G H T
Chimpanzee Pan troglodytes XP_512012 1846 210165 S772 Q T I V F L Y S L Y K E G H T
Rhesus Macaque Macaca mulatta XP_001111066 1981 224269 S777 Q T I V F L Y S L Y K E V L D
Dog Lupus familis XP_536627 1977 223828 S754 Q T I V F L Y S L Y K E G H T
Cat Felis silvestris
Mouse Mus musculus Q6PDQ2 1915 217732 S760 Q T A V F L Y S L Y K E G H S
Rat Rattus norvegicus Q9JIX5 2581 290674 E852 Q S I A F L Q E V Y N V G I H
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q06A37 3011 338194 E1010 Q S I T F L Y E I Y L K G I H
Frog Xenopus laevis NP_001080504 1893 214670 S758 Q T A V F L Y S L Y K E G H S
Zebra Danio Brachydanio rerio B0R0I6 2511 279693 E888 Q S I A L L S E M F S A G V Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O97159 1982 224182 S771 Q T V T F L Y S L Y K E G H C
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q22516 1787 205237 T657 Q S L T F L Y T L M K E G H T
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9S775 1384 158387 R362 A Q A R A V I R E H E F Y L S
Baker's Yeast Sacchar. cerevisiae P32657 1468 168223 E445 P A W L D T F E K W A P D L N
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 90.3 97.8 97.3 N.A. 67.6 22.6 N.A. N.A. 23.4 66 22.7 N.A. 55 N.A. 47.2 N.A.
Protein Similarity: 100 90.5 98.1 98 N.A. 78.3 37.6 N.A. N.A. 37.2 77.1 38.5 N.A. 68.6 N.A. 61.7 N.A.
P-Site Identity: 100 100 80 100 N.A. 86.6 40 N.A. N.A. 46.6 86.6 26.6 N.A. 80 N.A. 66.6 N.A.
P-Site Similarity: 100 100 80 100 N.A. 93.3 53.3 N.A. N.A. 66.6 93.3 46.6 N.A. 86.6 N.A. 86.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 29 26 N.A.
Protein Similarity: N.A. N.A. N.A. 42.6 40.2 N.A.
P-Site Identity: N.A. N.A. N.A. 0 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 24 16 8 0 0 0 0 0 8 8 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % C
% Asp: 0 0 0 0 8 0 0 0 0 0 0 0 8 0 8 % D
% Glu: 0 0 0 0 0 0 0 31 8 0 8 62 0 0 0 % E
% Phe: 0 0 0 0 77 0 8 0 0 8 0 8 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 77 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 8 0 0 0 54 16 % H
% Ile: 0 0 54 0 0 0 8 0 8 0 0 0 0 16 0 % I
% Lys: 0 0 0 0 0 0 0 0 8 0 62 8 0 0 0 % K
% Leu: 0 0 8 8 8 85 0 0 62 0 8 0 0 24 0 % L
% Met: 0 0 0 0 0 0 0 0 8 8 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 8 % N
% Pro: 8 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % P
% Gln: 85 8 0 0 0 0 8 0 0 0 0 0 0 0 8 % Q
% Arg: 0 0 0 8 0 0 0 8 0 0 0 0 0 0 0 % R
% Ser: 0 31 0 0 0 0 8 54 0 0 8 0 0 0 24 % S
% Thr: 0 54 0 24 0 8 0 8 0 0 0 0 0 0 31 % T
% Val: 0 0 8 47 0 8 0 0 8 0 0 8 8 8 0 % V
% Trp: 0 0 8 0 0 0 0 0 0 8 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 70 0 0 70 0 0 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _